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Simvastatin 40mg Tablets, 28 Tablets

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Reduces total cholesterol levels

Reduces both bad cholesterol (LDL) and triglycerides in the blood

Increase the levels of Good Cholesterol (HDL) in the blood

Active Ingredient: Simvastatin 40mg

2,500.00

Availability: In Stock
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Simvastatin 40mg Tablets, 28 Tablets

What is Simvastatin 40mg Tablets?

Simvastatin 40mg tablets contain the active substance simvastatin. Simvastatin is a medicine used to lower levels of total cholesterol, “bad” cholesterol (LDL cholesterol), and fatty substances called triglycerides in the blood. In addition Simvastatin raises levels of “good” cholesterol (HDL cholesterol). Simvastatin is a member of the class of medicines called statins.

What is Cholesterol?

Cholesterol is one of several fatty substances found in the bloodstream. Your total cholesterol is made up mainly of LDL and HDL cholesterol.
LDL cholesterol is often called “bad” cholesterol because it can build up in the walls of your arteries forming plaque. Eventually this plaque build-up can lead to a narrowing of the arteries.
This narrowing can slow or block blood flow to vital organs such as the heart and brain. This blocking of blood flow can result in a heart attack or stroke.
HDL cholesterol is often called “good” cholesterol because it helps keep the bad cholesterol from building up in the arteries and protects against heart disease.
Triglycerides are another form of fat in your blood that may increase your risk for heart disease.
You should stay on a cholesterol-lowering diet while taking this medicine.

What are triglycerides?

Triglycerides are a type of fat that we need to survive. They give our bodies energy and keep us healthy, but if there is too much in the bloodstream it can raise risks for heart disease or other conditions such as pancreatitis which causes inflammation near your stomach muscles (pancreas).

What is Simvastatin Used for?

Simvastatin is used in addition to your cholesterol lowering diet if you have:
• a raised cholesterol level in your blood (primary hypercholesterolaemia) or elevated fat levels in your blood (mixed hyperlipidaemia).
• a hereditary illness (homozygous familial hypercholesterolaemia) that increases the cholesterol level in your blood. You may also receive other treatments.
• coronary heart disease (CHD) or are at high risk of CHD (because you have diabetes, history of stroke, or other blood vessel disease). Simvastatin may prolong your life by reducing the risk of heart disease problems, regardless of the amount of cholesterol in your blood.
In most people, there are no immediate symptoms of high cholesterol. Your doctor can measure your cholesterol with a simple blood test. Visit your doctor regularly, keep track of your cholesterol, and discuss your goals with your doctor

Simvastatin 40mg Tablets Reviews

After using Simvastatin 40mg Tablets, it’s helpful to let others know about your experience. Reviews of an item help other users know that medicines received have helped the condition it is claimed for, how well the treatment worked or any issues to be aware of. We invite our users to leave a review of both their treatment and of the service provided. Click on the reviews tab to see if there has been feedback on this item.

What is the price of Simvastatin 40mg Tablets in Nigeria

The price of Simvastatin 40mg Tablets is N1000

Where can you buy Simvastatin 40mg Tablets In Nigeria?

You can Buy Simvastatin 40mg Tablets at Asset Pharmacy Lagos Nigeria, Nigeria’s Largest Online Pharmacy.

Simvastatin 40mg Tablets is a prescription drug that legally requires a medical prescription to be dispensed.
To order this product you confirm that you are under the care of your doctor or consultant and have been given permission by them for purchase, fulfillment & use in treatment with their written consent.

Brand

Simvastatin

How to Use

How to take Simvastatin 40mg Tablets

Your doctor will determine the appropriate tablet strength for you, depending on your condition,
your current treatment and your personal risk status.
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
You should stay on a cholesterol-lowering diet while taking simvastatin.
Dosage:
The recommended dose is simvastatin 5 mg, 10 mg, 20 mg, 40 mg, or 80 mg tablet by mouth once a day.
Adults:
The usual starting dose is 10, 20 or, in some cases, 40 mg a day. Your doctor may adjust your dose after at least 4 weeks to a maximum of 80 mg a day. Do not take more than 80 mg a day.
Your doctor may prescribe lower doses, particularly if you are taking certain medicinal products
listed above or have certain kidney conditions.
The 80 mg dose is only recommended for adult patients with very high cholesterol levels and at high risk of heart disease problems who have not reached their cholesterol goal on lower doses.
Use in children and adolescents:
For children (10 -17 years old), the recommended usual starting dose is 10 mg a day in the evening. The maximum recommended dose is 40 mg a day.
Method of administration:
Take simvastatin in the evening. You can take it with or without food. Keep taking Simvastatin unless your doctor tells you to stop.
If your doctor has prescribed Simvastatin along with another medicine for lowering cholesterol containing any bile acid sequestrant, you should take Simvastatin at least 2 hours before or 4 hours after taking the bile acid sequestrant.
If you take more simvastatin than you should
• Please contact your doctor or pharmacist.
If you forget to take simvastatin
• Do not take extra double dose to make up for a forgotten tablet just take your normal amount of Simvastatin at the usual time the next day.
If you stop taking simvastatin
• Talk to your doctor or pharmacist because your cholesterol may rise again.
If you have any further questions on the use of this product, ask your doctor or pharmacist.

Product Details

Product Information of Simvastatin 40mg Tablets

What you need to know before you take Simvastatin
Do not take Simvastatin
• if you are allergic (hypersensitive) to simvastatin or any of the other ingredients of this medicine (listed in section 6: Contents of the pack and other information).
• if you currently have liver problems
• if you are pregnant or breast-feeding
• if you are taking medicine(s) with one or more than one of the following active ingredients::
– itraconazole, ketoconazole, posaconazole or voriconazole (used to treat fungal infections)
– erythromycin, clarithromycin or telithromycin (used to treat infections)
– HIV protease inhibitors such as indinavir, nelfinavir, ritonavir, and saquinavir (HIV protease inhibitors are used for HIV infections)
– boceprevir or telaprevir (used to treat hepatitis C virus infection)
– nefazodone (used to treat depression)
– cobicistat
– gemfibrozil (used to lower cholesterol)
– ciclosporin (used in organ transplant patients)
– danazol (a man-made hormone used to treat endometriosis, a condition in which the lining of the uterus grows outside the uterus).
• if you are taking or have taken in the last 7 days, a medicine called fusidic acid (a medicine for bacterial infection) orally or by injection. The combination of fusidic acid and Simvastatin can lead to serious muscle problems (rhabdomyolysis)
• Do not take more than 40 mg Simvastatin if you are taking lomitapide (used to treat a serious and rare genetic cholesterol condition)
Ask your doctor if you are not sure if your medicine is listed above.
Warnings and precautions
Tell your doctor:
• about all your medical conditions including allergies.
• if you drink large amounts of alcohol.
• if you have ever had liver disease. Simvastatin may not be right for you.
• if you are due to have an operation. You may need to stop taking Simvastatin tablets for a short time.
• if you are Asian, because a different dose may be applicable to you.
• Your doctor should do a blood test before you start taking simvastatin and if you have any symptoms of liver problems while you take simvastatin. This is to check how well your liver is working.
• Your doctor may also want you to have blood tests to check how well your liver is working after you start taking simvastatin
• While you are on this medicine your doctor will monitor you closely if you have diabetes or are at risk of developing diabetes. You are likely to be at risk of developing diabetes if you have high levels of sugars and fats in your blood, are overweight and have high blood pressure.
• Tell your doctor if you have severe lung disease.
Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness. This is because on rare occasions, muscle problems can be serious, including muscle breakdown resulting in kidney damage; and very rare deaths have occurred.
The risk of muscle breakdown is greater at higher doses of simvastatin, particularly the 80-mg dose. The risk of muscle breakdown is also greater in certain patients. Talk with your doctor if any of the following applies:
• you consume large amounts of alcohol
• you have kidney problems
• you have thyroid problems
• you are 65 years or older
• you are female
• you have ever had muscle problems during treatment with cholesterol-lowering medicines called “statins” or fibrates
• you or a close family member have a hereditary muscle disorder.
Also tell your doctor or pharmacist if you have a muscle weakness that is constant. Additional tests and medicines may be needed to diagnose and treat this.
Children and adolescents
Safety and effectiveness of simvastatin have been studied in 10-17 year old boys and in girls who had started their menstrual period (menstruation) at least one year before (see section 3: How to take Simvastatin). Simvastatin has not been studied in children under the age of 10 years. For more information, talk to your doctor.
Other medicines and Simvastatin
Tell your doctor if you are taking, have recently taken or might take any other medicine(s) with any of the following active ingredients. Taking simvastatin with any of the following medicines can increase the risk of muscle problems (some of these have already been listed in the above section “Do not take Simvastatin.”)
• If you need to take oral fusidic acid to treat a bacterial infection you will need to temporarily stop using this medicine. Your doctor will tell you when it is safe to restart Simvastatin.
Taking Simvastatin with fusidic acid may rarely lead to muscle weakness, tenderness or pain (rhabdomyolysis). See more information regarding rhabdomyolysis in section 4.
• ciclosporin (often used in organ transplant patients),
• danazol (a man-made hormone used to treat endometriosis, a condition in which the lining of the uterus grows outside the uterus),
• medicines with an active ingredient like itraconazole, ketoconazole, fluconazole posaconazole, or voriconazole (used to treat fungal infections),
• fibrates with an active ingredient like gemfibrozil and bezafibrate (used to lower cholesterol),
• erythromycin, clarithromycin or telithromycin, (used to treat bacterial infections),
• HIV protease inhibitors such as indinavir, nelfinavir, ritonavir and saquinavir (used to treat AIDS),
• Hepatitis C antiviral agents such as boceprevir, telaprevir, elbasvir or grazoprevir (used to treat hepatitis C virus infection),
• nefazodone (used to treat depression),
• medicines with the active ingredient cobicistat
• amiodarone (used to treat an irregular heartbeat),
• verapamil, diltiazem or amlodipine (used to treat high blood pressure, chest pain associated with heart disease, or other heart conditions),
• lomitapide (used to treat a serious and rare genetic cholesterol condition),
• daptomycin (a drug used to treat complicated skin and skin structure infections and bacteraemia). It is possible that side effects affecting the muscles may be higher when this medicine is taken during treatment with simvastatin (e.g. simvastatin). Your doctor may decide that you stop taking simvastatin for a while,
• colchicine (used to treat gout),
As well as the medicines listed above, tell your doctor or pharmacist if you are taking, have recently taken any other medicines, including those obtained without a prescription. In particular, tell your doctor if you are taking medicine(s) with any of the following active ingredients:
• medicines with an active ingredient to prevent blood clots, such as warfarin phenprocoumon or acenocoumarol (anticoagulants).
• fenofibrate (also used to lower cholesterol).
• niacin (also used to lower cholesterol)
• rifampicin ( used to treat tuberculosis)
You should also tell any doctor who is prescribing a new medicine for you that you are taking simvastatin.
Simvastatin with food and drink
Grapefruit juice contains one or more components that alter how the body uses some medicinal products, including simvastatin. Consuming grapefruit juice should be avoided.
Pregnancy and breast-feeding
Do not take Simvastatin if you are pregnant, trying to get pregnant or think you may be pregnant.
If you get pregnant while taking Simvastatin, stop taking it immediately and contact your doctor.
Do not take Simvastatin if you are breast-feeding, because it is not known if the medicine is passed into breast milk.
Ask your doctor or pharmacist for advice before taking any medicine.
Driving and using machines
Simvastatin is not expected to interfere with your ability to drive or to use machinery. However, it
should be taken into account that some people get dizzy after taking simvastatin.
Simvastatin contains lactose
Simvastatin tablets contain a sugar called lactose. If you have been told by your doctor that you
have an intolerance to some sugars, contact your doctor before taking this medicinal product.

How to store Simvastatin
Keep this medicine out of the sight and reach of children.
This medicinal product does not require any special storage conditions.
Do not use this medicine after the expiry date which is stated on the blister and carton after EXP. The expiry date refers to the last day of that month.
Do not throw away any medicines via wastewater or household waste. Ask your
pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

Side Effects

Side Effects of Simvastatin 40mg Tablets

Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
The following terms are used to describe how often side effects have been reported:
Rare (may affect up to 1 of 1000 people),
Very rare (may affect up to 1 of 10,000 people),
Not known (frequency cannot be estimated from the available data),
If any of the below mentioned serious side effects happen, stop taking the medicine and tell your doctor immediately or go to the emergency room at your nearest hospital.
The following rare serious side effects were reported.
• muscle pain, tenderness, weakness, or cramps. On rare occasions, these muscle problems can be serious, including muscle breakdown resulting in kidney damage; and very rare deaths have occurred.
• hypersensitivity (allergic) reactions including:
• swelling of the face, tongue and throat which may cause difficulty in breathing
(angioedema)
• severe muscle pain usually in the shoulders and hips,
• rash with weakness of limbs and neck muscles,
• pain or inflammation of the joints (polymyalgia rheumatica),
• inflammation of the blood vessels (vasculitis),
• unusual bruising, skin eruptions and swelling (dermatomyositis), hives, skin sensitivity to the sun, fever, flushing,
• shortness of breath (dyspnoea) and feeling unwell,
• lupus-like disease picture (including rash, joint disorders, and effects on blood cells),
• inflammation of the liver with the following symptoms: yellowing of the skin and eyes, itching, dark-coloured urine or pale-coloured stool, feeling tired or weak, loss of appetite; liver failure (very rare),
• inflammation of the pancreas often with severe abdominal pain.
The following very rare serious side effect was reported:
• a serious allergic reaction which causes difficulty in breathing or dizziness (anaphylaxis)
• rash that may occur on the skin or sores in the mouth (lichenoid drug eruptions)
• muscle rupture
• gynecomastia (breast enlargement in men)
The following side effects have also been reported rarely:
• low red blood cell count (anaemia),
• numbness or weakness of the arms and legs,
• headache, tingling sensation, dizziness,
• digestive disturbances (abdominal pain, constipation, flatulence, indigestion, diarrhoea, nausea, vomiting),
• rash, itching, hair loss,
• weakness,
• trouble sleeping (very rare),
• poor memory (very rare), memory loss, confusion.
• blurred vision and impaired vision
The following side effects have also been reported but the frequency cannot be estimated from the available information (frequency not known):
• erectile dysfunction,
• depression,
• tendon problems, sometimes complicated by rupture of the tendon,
• inflammation of the lungs causing breathing problems including persistent cough and/or shortness of breath or fever.
Additional possible side effects reported with some statins:
• sleep disturbances, including nightmares,
• sexual difficulties,
• Diabetes. This is more likely if you have high levels of sugars and fats in your blood, are overweight and have high blood pressure. Your doctor will monitor you while you are taking this medicine.
• muscle pain, tenderness, or weakness that is constant that may not go away after stopping Simvastatin (frequency not known).
Laboratory Values
Elevations in some laboratory blood tests of liver function and a muscle enzyme (creatine kinase) have been observed.
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet

Ingredients

Product Ingredients of Simvastatin 40mg Tablets

Each film-coated tablet contains 40 mg simvastatin

The other ingredients are:
Tablet core:
Butylated hydroxyanisole (E320)
Ascorbic acid (E300)
Citric acid monohydrate (E330)
Microcrystalline cellulose (E460a)
Pregelatinised maize starch
Lactose monohydrate
Magnesium stearate (E470B)
Film coating:
Hypromellose (E464)
Hydroxypropyl cellulose (E463)
Titanium dioxide (E171)
Talc (E553b).
Iron oxide yellow (E 172) – For 10 and 20 mg

Patient Information Leaflet

Click here  for the Patient Information Leaflet of Simvastatin 40mg Tablets

Prescription Product

This product requires a prescription from your Doctor.

Please follow the instruction received from the pharmacy on how to forward your prescription to the pharmacy after you have paid for the medicine.

A prescription drug is a pharmaceutical medication that legally requires a medical prescription to be dispensed.
To order this product you confirm that you are under the care of your doctor or consultant and have been given permission by them for purchase, fulfillment & use in treatment with their written consent

Delivery

Delievry time are estimates. Can vary due to the time of day you order.

Delivery time estimate are subject to the courier company.

Shipping to Lagos cost starts from N1850 Next day delivery

Shipping to Rest Of Nigeria – 2-3 days cost starts from N2000

Shipping to Rest of Africa –  5-7 working days Cost starts from N12000

Shipping to Europe 7 – 14 working days Cost srats from N18000

Shipping to Rest of the world – 7 – 14 days Cost starts from N18000

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