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Exforge HCT 10mg/160mg/12.5mg Tablets, 28 Tablets
Exforge HCT 10mg/160mg/12.5mg Tablets contain three substances called amlodipine, valsartan and hydrochlorothiazide. All of these substances help to control high blood pressure.
Amlodipine belongs to a group of substances called calcium channel blockers?. Amlodipine stops calcium from moving into the blood vessel wall, which stops the blood vessels from tightening.
Valsartan belongs to a group of substances called angiotensin-II receptor antagonists?. Angiotensin II is produced by the body and makes the blood vessels tighten, thus increasing the blood pressure. Valsartan works by blocking the effect of angiotensin II.
Hydrochlorothiazide belongs to a group of substances called thiazide diuretics?. Hydrochlorothiazide increases urine output, which also lowers blood pressure. As a result of all three mechanisms, the blood vessels relax and blood pressure is lowered.
What is Exforge HCT 10mg/160mg/12.5mg Tablets used for?
Exforge HCT is used to treat high blood pressure in adult patients who are already taking amlodipine, valsartan and hydrochlorothiazide and who may benefit from taking one tablet containing all three substances.
What is High Blood Pressure?
High blood pressure often has little or no symptoms. But if untreated, it increases your risk of serious problems such as heart attacks and strokes which can have a devastating impact on quality of life. Around one third (33%) adults in the Nigeria are believed to have high levels without knowing about it because they do not experience any discomfort when resting; however this may change for some people who become more active than usual due to work stressors like anxiety at night time before bedtime etc.. The only way you will know whether or not your own personalised level falls into this category would be by having an assessment done through testing methods including purchasing medicine over-the counter from stores.
Blood pressure is recorded with 2 numbers. The systolic pressure (higher number) is the force at which your heart pumps blood around your body.
The diastolic pressure (lower number) is the resistance to the blood flow in the blood vessels.
They’re both measured in millimetres of mercury (mmHg).
As a general guide:
- high blood pressure is considered to be 140/90mmHg or higher (or 150/90mmHg or higher if you’re over the age of 80)
- ideal blood pressure is usually considered to be between 90/60mmHg and 120/80mmHg
Blood pressure readings between 120/80mmHg and 140/90mmHg could mean you’re at risk of developing high blood pressure if you do not take steps to keep your blood pressure under control.
Everyone’s blood pressure will be slightly different. What’s considered low or high for you may be normal for someone else.
If your blood pressure is too high, it puts extra strain on your blood vessels, heart and other organs, such as the brain, kidneys and eyes.
Persistent high blood pressure can increase your risk of a number of serious and potentially life-threatening health conditions, such as:
- heart disease
- heart attacks
- heart failure
- peripheral arterial disease
- aortic aneurysms
- kidney disease
- vascular dementia
If you have high blood pressure, reducing it even a small amount can help lower your risk of these health conditions.
It’s not always clear what causes high blood pressure, but there are things that can increase your risk.
You might be more at risk if you:
- are overweight
- eat too much salt and do not eat enough fruit and vegetables
- do not do enough exercise
- drink too much alcohol or coffee (or other caffeine-based drinks)
- do not get much sleep or have disturbed sleep
- are over 65
- have a relative with high blood pressure
- are of black African or black Caribbean descent
- live in a deprived area
Making healthy lifestyle changes can sometimes help reduce your chances of getting high blood pressure and help lower your blood pressure if it’s already high.
Exforge is available in different strengths, click here to view
Exforge HCT 10mg/160mg/12.5mg Tablets Reviews
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What is the price of Exforge HCT 10mg/160mg/12.5mg Tablets in Nigeria
The price of Exforge HCT 10mg/160mg/12.5mg Tablets is N10350
Where can you buy Exforge HCT 10mg/160mg/12.5mg Tablets In Nigeria?
You can Buy Exforge HCT 10mg/160mg/12.5mg Tablets at Asset Pharmacy Lagos Nigeria, Nigeria’s Largest Online Pharmacy.
How to Use
How to use Exforge HCT 10mg/160mg/12.5mg Tablets
Always take this medicine exactly as your doctor has told you. You should check with your doctor if you are not sure. This will help you get the best results and lower the risk of side effects.
The usual dose of Exforge HCT is one tablet per day.
- It is best to take the tablet at the same time each day. Morning is the best time.
- Swallow the tablet whole with a glass of water.
- You can take Exforge HCT with or without food.
Depending on how you respond to the treatment, your doctor may suggest a higher or lower dose.
If you take more Exforge HCT than you should
If you have accidentally taken too many Exforge HCT tablets, talk to a doctor immediately.You may require medical attention.
If you forget to take Exforge HCT
If you forget to take a dose of this medicine, take it as soon as you remember and then take the next dose at its usual time. If it is almost time for your next dose you should simply take the next tablet at the usual time. Do not take a double dose (two tablets at once) to make up for a forgotten tablet.
If you stop taking Exforge HCT
Stopping your treatment with Exforge HCT may cause your disease to get worse. Do not stop taking your medecine unless your doctor tells you to.
Always take this medicine, even if you are feeling well
People who have high blood pressure often do not notice any signs of the problem. Many feel normal. It is very important that you take this medicine exactly as your doctor tells you to get the best results and reduce the risk of side effects. Keep your appointments with the doctor even if you are feeling well.
If you have any further questions on the use of this product ask your doctor or pharmacist.
Product Information of Exforge HCT 10mg/160mg/12.5mg Tablets
Do not take Exforge HCT:
if you are more than 3 months pregnant (It is also better to avoid Exforge HCT in early pregnancy
if you are allergic (hypersensitive) to amlodipine, valsartan, hydrochlorothiazide, sulphonamide-derived medicines (medicines used to treat chest or urinary infections), or any of the other ingredients of Exforge HCT
If you think you may be allergic, do not take Exforge HCT and talk to your doctor.
if you have liver problems, such as liver disorders and jaundice (cholestasis).
if you have severe kidney problems or if you are having dialysis.
if you are suffering from an inability to produce urine.
if the level of potassium or sodium in your blood is too low despite treatment.
if the level of calcium in your blood is too high despite treatment.
if you have gout (uric acid crystals in the joints). If any of the above applies to you, do not take Exforge HCT and talk to your doctor.
Take special care with Exforge HCT
if you have a low level of potassium, sodium or magnesium in your blood.
if you have a high level of calcium in your blood.
- if you are taking medicines or substances that increase the amount of potassium in your blood. These include potassium supplements or salt substitutes containing potassium, potassium-sparing medicines and heparin. It may be necessary to check the amount of potassium in your blood at regular intervals.
- if you have kidney problems, have had a kidney transplant or if you had been told that you have a narrowing of your kidney arteries.
- if you have liver problems.
- if you have or have had heart failure or coronary arterydisease, particularly if you are taking the maximum dose of Exforge HCT (10 mg/320 mg/25 mg)
- if your doctor has told you that you have a narrowing of the valves in your heart
- if you suffer from aldosteronism. This is a disease in which the adrenal glands make too much of the hormone aldosterone If this applies to you, the use of Exforge HCT is not recommended.
- if you suffer from a disease called systemic lupus erythematosus
- if you have diabetes (high blood sugar).
- if you have high levels of cholesterol or triglycerides in your blood.
- if you experience skin reactions such as rash after sun exposure
- if you had an allergic reaction to other high blood pressure medicines or diuretics (a type of medicine also known as
- if you have been sick (vomiting or diarrhoea).
- if you experience dizziness and/or fainting during treatment with Exforge HCT, tell your doctor as soon as possible. If any of these apply to you, talk to your doctor.
You must tell your doctor if you think that you are ( or might become) pregnant. Exforge HCT is not recommended in early pregnancy and must not be taken if you are more than 3 months pregnant, as it may cause serious harm to your baby if used at this stage
The use of Exforge HCT in children and adolescents under 18 years of age is not recommended.
Exforge HCT and older people (age 65 years and older)
Exforge HCT can be used by people aged 65 years and over at the same dose as for other adults and in the same way as they have already taken the three substances called amlodipine, valsartan and hydrochlorothiazide. Elderly patients, particularly those taking the maximum dose of Exforge HCT (10 mg/320 mg/25 mg), should have their blood pressure checked regularly.
Using other medicines
Please tell your doctor or pharmacist if you are using or have recently used any other medicine, including medicines obtained without a prescription. Your doctor may need to change the dose or take other precautions. In some cases you may have to stop using one of the medicines. This is especially important if you are using any of the medicines listed below:
Do not take together with:
- lithium (a medicine used to treat some types of depression);
- medicines or substances that increase the amount of potassium in your blood. These include potassium supplements or salt substitutes containing potassium, potassium-sparing medicines and heparin. Caution should be used with:
- alcohol, sleeping pills and anaesthetics (medicines allowing patients to undergo surgery and other procedures);
- allopurinol (anti-gout treatment);
- amantadine (anti-Parkinson therapy, also used for influenza treatment);
- anticholinergic agents (medicines used to treat a variety of disorders such as gastrointestinal cramps, urinary bladder spasm, asthma, motion sickness, muscular spasms, Parkinson’s disease and as an aid to anaesthesia);
- anticonvulsant medicines and mood-stabilising medicines used to treat epilepsy and bipolar disorder (e.g. carbamazepine, phenobarbital, phenytoin, fosphenytoin, primidone);
- cholestyramine and colestipol (substances used mainly to treat high levels of lipids in the blood);
- ciclosporin (a medicine used in transplantation to prevent organ rejection or for other conditions, e.g: rheumatoid arthritis or atopic dermatitis);
- cortisone-like medicines, steroids;
- curare derivatives (a medicine to relax the muscles which is used during operations);
- cytotoxic medicines (used to treat cancer);
- digoxin (a heart medicine);
- medicines for the treatment of diabetes (oral agents such as metformin or insulins);
- medicines to increase blood pressure (adrenaline, noradrenaline);
- medicines used for HIV/AIDS (e.g. ritonavir) or for treatment of fungal infections (e.g. ketoconazole);
- medicines used for oesophageal ulceration and inflammation (carbenoxolone);
- medicines used to relieve pain or inflammation, especially non-steroidal anti-inflammatory agents;
- nitroglycerin and other nitrates, or other substances called ?vasodilators?;
- other medicines to treat high blood pressure (beta blockers, diazoxides, methyldopa);
- rifampicin (used, for example, to treat tuberculosis);
- some medicines used to treat infections such as amphotericin, penicillin G, tetracycline;
- St. John?s wort;
- vitamin D and calcium salts. Talk to your doctor before drinking alcohol. Alcohol may make your blood pressure fall too much and/or increase the possibility of dizziness or fainting.
Taking Exforge HCT with food and drink
You can take Exforge HCT with or without food.
Pregnancy and breast-feeding
You must tell your doctor if you think you are ( or might become) pregnant. Your doctor will normally advise you to stop taking Exforge HCT before you become pregnant or as soon as you know you are pregnant and will advise you to take another medicine instead of Exforge HCT. Exforge HCT is not recommended in early pregnancy and must not be taken if you are more than 3 months pregnant, as it may cause serious harm to your baby if it is used after the third month of pregnancy.
Breast-feedingTell your doctor if you are breast-feeding or about to start breast-feeding. Exforge HCT is not recommended for mothers who are breast-feeding, and your doctor may choose another treatment for you if you wish to breast-feed, especially if your baby is a newborn, or was born prematurely.
Ask your doctor or pharmacist for advice before taking any medicine.
Driving and using machines
As with many other medicines used to treat high blood pressure, this medicine may make you feel dizzy. If you experience this symptom, do not drive or use tools or machines.
How should it be stored?
Keep out of the reach and sight of children.
Do not use Exforge HCT after the expiry date which is stated on the carton and blister after EXP. The expiry date refers to the last day of that month.
Do not store above 30°C.
Store in the original package in order to protect from moisture.
Do not use any Exforge HCT pack that is damaged or shows signs of tampering.
Side Effects of Exforge HCT 10mg/160mg/12.5mg Tablets
Like all medicines, Exforge HCT can cause side effects, although not everybody gets them. These side effects may occur with certain frequencies, which are defined as follows: very common: affects more than 1 user in 10
common: affects 1 to 10 users in 100
uncommon: affects 1 to 10 users in 1,000
rare: affects 1 to 10 users in 10,000
very rare: affects less than 1 user in 10,000
not known: frequency cannot be estimated from the available data
Some side effects can be serious and need immediate medical attention:
You should see your doctor immediately if you experience any of the following symptoms: Common
- low blood pressure (feeling of faintness, light-headedness, sudden loss of consciousness) Uncommon
- severely decreased urine output (decreased kidney function) Rare
- spontaneous bleeding
- irregular heart beat
- liver disorder Very rare
- allergic reaction with symptoms such as rash, itching
- angioedema: swelling of face or lips or tongue, difficulty of breathing
- crushing/tight chest pain that gets worse or that does not go away
- weakness, bruising, fever and frequent infections
Other possible side effects of Exforge HCT:
Common: Stomach discomfort after meal; tiredness; swelling; low level of potassium in the blood; headache; frequent urination.
Uncommon: Fast heart beat; spinning sensation; vision disorder; stomach discomfort; chest pain; increase of urea nitrogen, creatinine and uric acid in the blood; high level of calcium fat or sodium in the blood; decrease of potassium in the blood; breath odour; diarrhoea; dry mouth; nausea; vomiting; abdominal pain; weight increase; loss of appetite; disturbed sense of taste; back pain; joint swelling; muscle cramps/weakness/pain; pain in extremity; inability to either stand or walk in a normal manner; weakness; abnormal coordination; dizziness on standing up or after exercising; lack of energy; sleep disturbances; tingling or numbness; neuropathy; sleepiness; sudden, temporary loss of consciousness; low blood pressure on standing up; impotence; cough; breathlessness; throat irritation; excessive sweating; itching; swelling, reddening and pain along a vein; skin reddening; trembling. Not known: Changes in blood tests for kidney function, increase of potassium in your blood, low level of red blood cells.
Side effects reported with amlodipine or valsartan or hydrochlorothiazide alone, but not observed with Exforge HCT or observed in a higher frequency:
AmlodipineCommon: Palpitations; abdominal pain; nausea; sleepiness; hot flushes.
Uncommon: Ringing noise in ears; change of bowel habit; pain; weight decrease; joint pain; trembling; mood swings; urination disorders; urination at night; breast enlargement in men; runny nose; hair loss; skin eruption; purple skin patches; rash; skin discoloration.
Very rare: Low level of white blood cells and blood platelets; irregular heart beat; heart attack; inflammation of the stomach lining or of the pancreas, gingival overgrowth, abnormal liver function test; liver disorder which can occur together with yellow skin and eyes, or dark-coloured urine; allergic reaction including swelling deeper in the skin and difficulty breathing; high level of sugar in the blood; increased muscle stiffness; skin reaction with skin reddening and peeling, blistering of lips, eyes or mouth; itchy rash; inflammation of blood vessels.
Not known: Stiff limbs and trembling hands.
ValsartanNot known: Abnormal red blood cell test; low level of a certain type of white blood cell and blood platelet; increase of potassium in the blood; increase of creatinine in the blood; abnormal liver function test; allergic reaction including swelling deeper in the skin and difficulty breathing; muscle pain; severely decreased urine output; itching; rash; inflammation of blood vessels.
HydrochlorothiazideCommon: Increase of lipids in the blood.
Uncommon: Low level of magnesium in the blood; rash; itchy rash.
Rare: Low level of blood platelets, sugar in the urine; high level of sugar in the blood; depression; irregular heart beat; abdominal discomfort; constipation; liver disorder which can occur together with yellow skin and eyes, or dark-coloured urine; increased sensitivity of skin to sun; purple skin patches. Very rare: Lack or low level of white blood cells; haemolytic anaemia (abnormal breakdown of red blood cells either in the blood vessels or elsewhere in the body); inflammation of the pancreas; allergic reaction; difficulty breathing, breathlessness; inflammation of the lungs, lupus erythematosus; inflammation of blood vessels; severe skin disease that causes rash, red skin, blistering of the lips, eyes or mouth, skin peeling, fever.
If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
Product Ingredients of Exforge HCT 10mg/160mg/12.5mg Tablets
What Exforge HCT contains
- The active substances of Exforge HCT are amlodipine (as amlodipine besylate), valsartan and hydrochlorothiazide.
- Exforge HCT 10 mg/160 mg/12.5 mg film-coated tablets: Each film-coated tablet contains 10 mg amlodipine (as amlodipine besylate),160 mg valsartan, and 12.5 mg hydrochlorothiazide. The other ingredients are cellulose microcrystalline; crospovidone; silica, colloidal anhydrous; magnesium stearate; hypromellose, macrogol 4000, talc, titanium dioxide (E171), yellow iron oxide (E172), red iron oxide (E172).
This product requires a prescription from your Doctor.
Please follow the instruction received from the pharmacy on how to forward your prescription to the pharmacy after you have paid for the medicine.
A prescription drug is a pharmaceutical medication that legally requires a medical prescription to be dispensed.
To order this product you confirm that you are under the care of your doctor or consultant and have been given permission by them for purchase, fulfillment & use in treatment with their written consent
Delievry time are estimates. Can vary due to the time of day you order.
Delivery time estimate are subject to the courier company.
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