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- Additional information
- How to Use
- Product Details
- Side Effects
- How to store
- Patient Information Leaflet
- Prescription Product
Plagerine 75mg Tablets – Clopidogrel Tablet, 30 Tablets
If you’re looking for an effective way to prevent blood clots, then Plagerine 75mg Tablets are the right choice for you. Containing clopidogrel 75mg, these tablets belong to a group of medicines known as antiplatelet medicinal products. They work by preventing blood clots from forming in hardened blood vessels, which can lead to serious atherothrombotic events such as stroke, heart attack, or death. Plagerine 75mg Tablets are taken by adults and have been proven to be an effective way to reduce the risk of these potentially life-threatening events. So if you’re looking for a safe and reliable way to protect yourself from atherothrombosis, then Plagerine 75mg Tablets are the perfect solution.
Plagerine 75mg Tablets Reviews
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What is the price of Plagerine 75mg Tablets – Clopidogrel Tablet in Nigeria?
The price of Plagerine 75mg Tablets – Clopidogrel Tablet is N2,300
Where can you buy Plagerine 75mg Tablets – Clopidogrel Tablet In Nigeria?
You can Buy Plagerine 75mg Tablets – Clopidogrel Tablet at Asset Pharmacy Lagos Nigeria, Nigeria’s Largest Online Pharmacy.
Plagerine 75mg Tablets – Clopidogrel Tablet is not available to buy over the counter. You need a prescription to buy Plagerine 75mg Tablets – Clopidogrel Tablet
Plagerine 75mg Tablets – Clopidogrel Tablet is a prescription drug that legally requires a medical prescription to be dispensed.
To order this product you confirm that you are under the care of your doctor or consultant and have been given permission by them for purchase, fulfillment & use in treatment with their written consent.
You will be required to send Asset Pharmacy your prescription
How to Use
How To Use Clopidogrel Tablets 75mg
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
The recommended dose, including for patients with a condition called ‘atrial fibrillation’ (an irregular heartbeat), is one 75 mg tablet of Clopidogrel per day to be taken orally with or without food, and at the same time each day.
If you have experienced severe chest pain (unstable angina or heart attack), your doctor may give you 300 mg or 600mg of Clopidogrel (4 or 8 tablets of 75 mg) once at the start of treatment. Then, the recommended dose is one 75 mg tablet of Clopidogrel per day as described above.
If you have experienced symptoms of a stroke which go away within a short period of time (also known as transient ischemic attack) or an ischemic stroke mild in severity, your doctor may give you 300 mg of Clopidogrel (4 tablets of 75 mg) once at the start of treatment. Then, the recommended dose is one 75 mg tablet of Clopidogrel per day as described above with acetylsalicylic acid for 3 weeks. Then the physician would prescribe either Clopidogrel alone or acetylsalicylic acid alone.
You should take Clopidogrel for as long as your doctor continues to prescribe it.
Product Information of Clopidogrel Tablets 75mg
What you need to know before you take Clopidogrel
Do not take Clopidogrel
- If you are allergic (hypersensitive) to clopidogrel or any of the other ingredients of this medicine (listed in section 6).
- If you have a medical condition that is currently causing bleeding such as a stomach ulcer or bleeding within the brain;
- If you suffer from severe liver disease.
If you think any of these apply to you, or if you are in any doubt at all, consult your doctor before taking Clopidogrel.
Warnings and precautions
Talk to your doctor or pharmacist before taking Clopidogrel:
- if you have a risk of bleeding such as
- a medical condition that puts you at risk of internal bleeding (such as a stomach ulcer).
- a blood disorder that makes you prone to internal bleeding (bleeding inside any tissues, organs or joints of your body).
- a recent serious injury.
- a recent surgery (including dental).
- a planned surgery (including dental) in the next seven days.
- if you have had a clot in an artery of your brain (ischemic stroke) which occurred within the last seven days.
- if you have kidney or liver disease.
- if you have had an allergy or reaction to any medicine used to treat your disease.
- if you had a past medical history of non-traumatic brain hemorrhage.
While you are taking Clopidogrel:
- You should tell your doctor if a surgery (including dental) is planned.
- You should also tell your doctor immediately if you develop a medical condition (also known as Thrombotic Thrombocytopenic Purpura or TTP) that includes fever and bruising under the skin that may appear as red pinpoint dots, with or without unexplained extreme tiredness, confusion, yellowing of the skin or eyes (jaundice) (see section 4 ‘Possible side effects’).
- If you cut or injure yourself, it may take longer than usual for bleeding to stop. This is linked to the way your medicine works as it prevents the ability of blood clots to form. For minor cuts and injuries e.g. cutting yourself shaving, this is usually of no concern. However, if you are concerned by your bleeding, you should contact your doctor straightaway (see section 4 ‘Possible side effects’).
- Your doctor may order blood tests.
Children and adolescents
Do not give this medicine to children because it does not work.
Other medicines and Clopidogrel
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription. Some other medicines may influence the use of Clopidogrel or vice versa.
You should specifically tell your doctor if you take
- medicines that may increase your risk of bleeding such as:
- oral anticoagulants, medicines used to reduce blood clotting.
- a non-steroidal anti-inflammatory medicine, usually used to treat painful and/or inflammatory conditions of muscle or joints.
- heparin or any other injectable medicine used to reduce blood clotting.
- ticlopidine, other antiplatelet agent.
- a selective serotonin reuptake inhibitor (including but not restricted to fluoxetine or fluvoxamine), medicines usually used to treat depression.
- rifampicin (used to treat severe infections).
- omeprazole or esomeprazole, medicines to treat upset stomach.
- fluconazole or voriconazole, medicines to treat fungal infections.
- efavirenz, or other anti-retroviral medicines (used to treat HIV infections).
- carbamazepine, a medicine to treat some forms of epilepsy.
- moclobemide, medicine to treat depression.
- repaglinide, medicine to treat diabetes.
- paclitaxel, medicine to treat cancer.
- opioids: while you are treated with clopidogrel, you should inform your doctor before being prescribed any opioid (used to treat severe pain).
- rosuvastatin (used to lower your cholesterol level).
If you have experienced severe chest pain (unstable angina or heart attack), transient ischemic attack or ischemic stroke in mild severity, you may be prescribed Clopidogrel in combination with acetylsalicylic acid, a substance present in many medicines used to relieve pain and lower fever. An occasional use of acetylsalicylic acid (no more than 1,000 mg in any 24 hour period) should generally not cause a problem, but prolonged use in other circumstances should be discussed with your doctor.
Clopidogrel with food and drink
Clopidogrel may be taken with or without food.
Pregnancy and breast-feeding
It is preferable not to take this product during pregnancy. If you are pregnant or suspect that you are pregnant, you should tell your doctor or your pharmacist before taking Clopidogrel. If you become pregnant while taking Clopidogrel, consult your doctor immediately as it is recommended not to take clopidogrel while you are pregnant.
You should not breast-feed while taking this medicine. If you are breast-feeding or planning to breast-feed, talk to your doctor before taking this medicine.
Ask your doctor or pharmacist for advice before taking any medicine.
Driving and using machines
Clopidogrel is unlikely to affect your ability to drive or to use machines.
Clopidogrel contains lactose. If you have been told by your doctor that you have an intolerance to some sugars (e.g. lactose), contact your doctor before taking this medicinal product.
Clopidogrel contains hydrogenated castor oil
This may cause stomach upset or diarrhoea.
Side Effects of Clopidogrel Tablets 75mg
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Contact your doctor immediately if you experience:
- fever, signs of infection or extreme tiredness. These may be due to rare decrease of some blood cells.
- signs of liver problems such as yellowing of the skin and/or the eyes (jaundice), whether or not associated with bleeding which appears under the skin as red pinpoint dots and/or confusion (see section 2 ’Warnings and precautions‘).
- swelling in the mouth or skin disorders such as rashes and itching, blisters of the skin. These may be the signs of an allergic reaction.
The most common side effect reported with Clopidogrel is bleeding. Bleeding may occur as bleeding in the stomach or bowels, bruising, haematoma (unusual bleeding or bruising under the skin), nose bleed, blood in the urine. In a small number of cases, bleeding in the eye, inside the head, the lung or the joints has also been reported.
If you experience prolonged bleeding when taking Clopidogrel
If you cut or injure yourself, it may take longer than usual for bleeding to stop. This is linked to the way your medicine works as it prevents the ability of blood clots to form. For minor cuts and injuries e.g. cutting yourself shaving, this is usually of no concern. However, if you are concerned by your bleeding, you should contact your doctor straightaway (see section 2 ‘Warnings and precautions’).
Other side effects include:
Common side effects (may affect up to 1 in 10 people): Diarrhoea, abdominal pain, indigestion or heartburn.
Uncommon side effects (may affect up to 1 in 100 people): Headache, stomach ulcer, vomiting, nausea, constipation, excessive gas in stomach or intestines, rashes, itching, dizziness, sensation of tingling and numbness.
Rare side effect (may affect up to 1 in 1,000 people): Vertigo, enlarged breasts in males.
Very rare side effects (may affect up to 1 in 10,000 people): Jaundice; severe abdominal pain with or without back pain; fever, breathing difficulties sometimes associated with cough; generalised allergic reactions (for example, overall sensation of heat with sudden general discomfort until fainting); swelling in the mouth; blisters of the skin; skin allergy; sore mouth (stomatitis); decrease in blood pressure; confusion; hallucinations; joint pain; muscular pain; changes in taste or loss of taste of food.
Side effects with frequency not known (frequency cannot be estimated from the available data):
Hypersensitivity reactions with chest or abdominal pain, persistent low blood sugar symptoms.
In addition, your doctor may identify changes in your blood or urine test results.
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
By reporting side effects, you can help provide more information on the safety of this medicine.
Ingredients of Clopidogrel Tablets 75mg
The active substance is clopidogrel. Each tablet contains 75 mg of clopidogrel (as hydrogen sulfate).
The other ingredients are mannitol (E421), hydrogenated castor oil, microcrystalline cellulose, macrogol 6000 and low-substituted hydroxypropylcellulose in the tablet core, and lactose monohydrate (milk sugar), hypromellose (E464), triacetin (E1518), iron oxide red (E172), titanium dioxide (E171), and carnauba wax in the tablet coating.
How to store
How to Store Clopidogrel Tablets 75mg
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the carton and on the blister, after EXP. The expiry date refers to the last day of that month.
Glass bottle: Store in the original package in order to protect from moisture.
After opening store at temperature below 25°C and use within 3 months.
PVC/PVDC/Aluminium blister: Store below 30°C in the original package in order to protect from moisture.
Do not use this medicine if you notice any visible sign of deterioration.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
Patient Information Leaflet
Please read before using the product
This product requires a prescription from your Doctor.
Please follow the instruction received from the pharmacy on how to forward your prescription to the pharmacy after you have paid for the medicine.
A prescription drug is a pharmaceutical medication that legally requires a medical prescription to be dispensed.
To order this product you confirm that you are under the care of your doctor or consultant and have been given permission by them for purchase, fulfillment & use in treatment with their written consent
Delievry time are estimates. Can vary due to the time of day you order.
Delivery time estimate are subject to the courier company.
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